KMID : 1001920130540060496
|
|
Journal of Korean Neurosurgical Society 2013 Volume.54 No. 6 p.496 ~ p.500
|
|
The Impact of Menopause on Bone Fusion after the Single-Level Anterior Cervical Discectomy and Fusion
|
|
Park Sung-Bae
Chung Chun-Kee Lee Sang-Hyung Yang Hee-Jin Son Young-Je Chung Young-Seob
|
|
Abstract
|
|
|
Objective: To evaluate the successful fusion rate in postmenopausal women with single-level anterior cervical discectomy and successful fusion (ACDF) and identify the significant factors related to bone successful fusion in pre- and postmenopausal women.
Methods: From July 2004 to December 2010, 108 consecutive patients who underwent single-level ACDF were prospectively selected as candidates. Among these, the charts and radiological data of 39 women were reviewed retrospectively. These 39 women were divided into two groups : a premenopausal group (n=11) and a postmenopausal group (n=28). To evaluate the significant factors affecting the successful fusion rate, the following were analyzed : the presence of successful fusion, successful fusion type, age, operated level, bone mineral density, graft materials, stand-alone cage or plating with autologous iliac bone, subsidence, adjacent segment degeneration, smoking, diabetes mellitus, and renal disease.
Results: The successful fusion rates of the pre- and postmenopausal groups were 90.9% and 89.2%, respectively. There was no significant difference in the successful fusion rate or successful fusion type between the two groups. In the postmenopausal group, three patients (10.8%) had successful fusion failure. In the postmenopausal group, age and subsidence significantly affected the successful fusion rate (p=0.016 and 0.011, respectively), and the incidence of subsidence in patients with a cage was higher than that in patients with a plate (p=0.030).
Conclusion: Menopausal status did not significantly affect bone successful fusion in patients with single-level ACDF. However, in older women with single-level ACDF, the combination of use of a cage and subsidence may unfavorably affect successful fusion.
|
|
KEYWORD
|
|
Menopause, Cervical, Discectomy, Successful fusion, Bone mineral density
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|